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Editorial Board
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| Introduction |
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Improving the clinical effectiveness of antidepressant treatment
The limitations of currently available antidepressants and, perhaps more importantly, the limitations of their use in day-to-day practice have been the focus of numerous publications. In this suppleme...
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Sidney H. Kennedy
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S1-S2
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| Review |
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Clinical effectiveness, construct and assessment
Abstract: Background: In an era of contention about the efficacy of antidepressants, the concept of clinical effectiveness has surfaced as a basic tenet of real-world practice. The concept of clinical...
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Scott Patten,
Sophie Grigoriadis,
Serge Beaulieu
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S3-S8
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| Research reports |
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Clinical effectiveness: The importance of psychosocial functioning outcomes
Abstract: Background: Major depressive disorder (MDD) is associated with significant impairment in quality of life and psychosocial functioning, including social and occupational/role functioning. Eva...
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Raymond W. Lam,
Marie-Josée Filteau,
Roumen Milev
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S9-S13
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Barriers to achieving treatment goals: A focus on sleep disturbance and sexual dysfunction
Abstract: Background: Patients who meet the criteria for a major depressive episode experience a constellation of symptoms, and different symptom configurations may reflect distinct underlying neurolo...
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Rachel Morehouse,
Glenda MacQueen,
Sidney H. Kennedy
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S14-S20
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Strategies to achieve clinical effectiveness: Refining existing therapies and pursuing emerging targets
Abstract: Background: Clinical effectiveness reflects a balance between efficacy and tolerability as well as patient satisfaction and overall improvement in quality of life and function. This is of pa...
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Sidney H. Kennedy,
Allan H. Young,
Pierre Blier
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S21-S28
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