| Reviews |
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Medial prefrontal cortex and the self in major depression
Abstract: Self-focus (i.e. the process by which one engages oneself in self-referential processing) is a core issue in the psychopathology of major depression. The cortical midline structures, includi...
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Cédric Lemogne,
Pauline Delaveau,
Maxime Freton,
Sophie Guionnet,
Philippe Fossati
et al.
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e1-e11
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Bipolarity and inadequate response to antidepressant drugs: Clinical and psychopharmacological perspective
Abstract: Objectives: The reason why depression may respond poorly to treatment with antidepressant drugs may be connected with the features of bipolarity. Evidence to this effect has accumulated in r...
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Janusz K. Rybakowski
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e13-e19
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Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association
Abstract: Background: Antidepressants can trigger a rapid mood switch from depression to mania. Identifying genetic risk factors associated with antidepressant induced mania (AIM) may enable individua...
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Joanna M. Biernacka,
Susan L. McElroy,
Scott Crow,
Alexis Sharp,
Joachim Benitez,
Marin Veldic,
Simon Kung,
Julie M. Cunningham,
Robert M. Post,
David Mrazek,
Mark A. Frye
et al.
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e21-e29
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The efficacy of zinc supplementation in depression: Systematic review of randomised controlled trials
Abstract: Background: Depression is a significant public health problem. Pre-clinical studies suggest a potential role of zinc in reducing or preventing depressive symptoms. Many epidemiological studi...
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Jun Lai,
Annette Moxey,
Gabriel Nowak,
Khanrin Vashum,
Kylie Bailey,
Mark McEvoy
et al.
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e31-e39
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| Research reports |
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The influence of affective temperaments and psychopathological traits on the definition of bipolar disorder subtypes: A study on Bipolar I Italian National sample
Abstract: Affective temperament and psychopathological traits such as separation anxiety (SA) and interpersonal sensitivity (IPS) are supposed to impact on the clinical manifestation and on the course...
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G. Perugi,
C. Toni,
I. Maremmani,
G. Tusini,
S. Ramacciotti,
A. Madia,
M. Fornaro,
H.S. Akiskal
et al.
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e41-e49
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Evaluation of the efficacy and safety of paliperidone extended-release in the treatment of acute mania: A randomized, double-blind, dose-response study
Abstract: Background: Atypical antipsychotics are effective in the treatment of bipolar I disorder. In this 3-week double-blind study, the efficacy and safety of paliperidone extended-release (ER) tab...
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Joris Berwaerts,
Haiyan Xu,
Isaac Nuamah,
Pilar Lim,
David Hough
et al.
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e51-e60
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Two-year outcomes in first-episode psychotic depression: The McLean–Harvard first-episode project
Abstract: Objective: Early assessment can guide accurate diagnosis, prognosis, and treatment-planning for patients with major mental illnesses. Longitudinal studies in psychotic depression from onset ...
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Mauricio Tohen,
Hari-Mandir K. Khalsa,
Paola Salvatore,
Eduard Vieta,
Caitlin Ravichandran,
Ross J. Baldessarini
et al.
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1-8
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Preference of lethal methods is not the only cause for higher suicide rates in males
Abstract: Background: In most countries worldwide suicide rates are higher for males whereas attempted suicide rates are higher for females. The aim is to investigate if the choice of more lethal meth...
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Anna Cibis,
Roland Mergl,
Anke Bramesfeld,
David Althaus,
Günter Niklewski,
Armin Schmidtke,
Ulrich Hegerl
et al.
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9-16
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Perfectionism dimensions in major postpartum depression
Abstract: Background: Although perfectionism from a multidimensional perspective has generally been associated with depressive illness, there are not many studies on its role in major depression in th...
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Estel Gelabert,
Susana Subirà,
Lluisa García-Esteve,
Purificación Navarro,
Anna Plaza,
Elisabet Cuyàs,
Ricard Navinés,
Mònica Gratacòs,
Manuel Valdés,
Rocío Martín-Santos
et al.
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17-25
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Type D (distressed) personality is associated with poor quality of life and mental health among 3080 cancer survivors
Abstract: Background: This study assessed the association between Type D personality (the conjoint effect of negative affectivity and social inhibition) and quality of life (QoL) and mental health of ...
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Floortje Mols,
Melissa S.Y. Thong,
Lonneke V. van de Poll-Franse,
Jan Anne Roukema,
Johan Denollet
et al.
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26-34
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Sociodemographic and psychopathological risk factors in repeated suicide attempts: Gender differences in a prospective study
Abstract: Background: The prevention of the repetition of suicide attempts is an important feature of the care of attempters but current data fail to give actual predictors of repetition. The aim of t...
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Julie Monnin,
Emilie Thiemard,
Pierre Vandel,
Magali Nicolier,
Gregory Tio,
Philippe Courtet,
Frank Bellivier,
Daniel Sechter,
Emmanuel Haffen
et al.
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35-43
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Offspring of parents with recurrent depression: Which features of parent depression index risk for offspring psychopathology?
Abstract: Background: Parental depression is associated with an increased risk of psychiatric disorder in offspring, although outcomes vary. At present relatively little is known about how differences...
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Becky Mars,
Stephan Collishaw,
Daniel Smith,
Ajay Thapar,
Robert Potter,
Ruth Sellers,
Gordon T. Harold,
Nicholas Craddock,
Frances Rice,
Anita Thapar
et al.
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44-53
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Impact on prisoners of participating in research interviews related to near-lethal suicide attempts
Abstract: Background: Prisoners have a high risk of suicide. Research studies have investigated factors contributing to this, some through interviews with survivors of suicide attempts, others with in...
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Adrienne Rivlin,
Lisa Marzano,
Keith Hawton,
Seena Fazel
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54-62
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Screening for depression in a sample of Egyptian secondary school female students
Abstract: Background: Depression is common in female adolescents. Data on prevalence rates, socio-demographic correlates, and putative risk factors in Egyptian population are needed along with better ...
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A. El-Missiry,
M. Soltan,
M. Abdel Hadi,
W. Sabry
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e61-e68
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Principal domains of quantitative anxiety trait in subjects with lifetime history of mania
Abstract: Background: High comorbidity rates for anxiety have been documented in subjects with history of mania or hypomania. We explored the presence of latent constructs of quantitative anxiety in s...
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Javier Contreras,
Elizabeth Hare,
Michael Escamilla,
Henriette Raventos
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e69-e75
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Ruminative response in clinical patients with major depressive disorder, bipolar disorder, and anxiety disorders
Abstract: Background: There is a growing interest in the transdiagnostic trait of rumination. However, few studies have directly examined the ruminative response in the diagnosis of disorders other th...
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Sojung Kim,
Bum Hee Yu,
Dong Soo Lee,
Ji-Hae Kim
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e77-e81
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Dysregulated glutamate and dopamine transporters in postmortem frontal cortex from bipolar and schizophrenic patients
Abstract: Background: Dysregulated glutamate, serotonin and dopamine neurotransmission has been reported in bipolar disorder (BD) and schizophrenia (SZ), but the underlying mechanisms of dysregulation...
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Jagadeesh Sridhara Rao,
Matthew Kellom,
Edmund Arthur Reese,
Stanley Isaac Rapoport,
Hyung-Wook Kim
et al.
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63-71
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The effects of blue-enriched light treatment compared to standard light treatment in seasonal affective disorder
Abstract: Background: One of the most frequently investigated hypotheses of the pathophysiology underlying Seasonal Affective Disorder (SAD) is a disturbance of circadian rhythms. Since the circadian ...
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M.C.M. Gordijn,
D. 't Mannetje,
Y. Meesters
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72-80
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Empirically derived subgroups of bipolar I patients with different comorbidity patterns of anxiety and substance use disorders in Han Chinese population
Abstract: Objective: Bipolar-I disorder (BPI) often co-occurred with anxiety (ANX) and substance use disorders (SUD), which poses challenges in public health and clinical treatment, and adds complexit...
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Han-Chieh Tsai,
Ming-Kun Lu,
Yen-Kuang Yang,
Ming-Chyi Huang,
Tzung-Lieh Yeh,
Wei-Jen Chen,
Ru-Band Lu,
Po-Hsiu Kuo
et al.
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81-89
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Social anxiety in the general population: Introducing abbreviated versions of SIAS and SPS
Abstract: Background: Social anxiety is characterized by the experience of stress, discomfort and fear in social situations, and is associated with substantial personal and societal burden. Two questi...
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Nina Kupper,
Johan Denollet
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90-98
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Decreased serotonin content and reduced agonist-induced aggregation in platelets of patients chronically medicated with SSRI drugs
Abstract: Background: Chronic treatment with selective serotonin reuptake inhibitors (SSRIs) reduces the risk and severity of cardiovascular diseases. SSRIs block the serotonin transporter, thereby in...
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Yona Bismuth-Evenzal,
Yehudit Gonopolsky,
David Gurwitz,
Iulian Iancu,
Abraham Weizman,
Moshe Rehavi
et al.
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99-103
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Validation of three psychometric instruments for screening for perinatal common mental disorders in men in the north of Vietnam
Abstract: Background: Perinatal non-psychotic common mental disorders (PCMDs) are less well recognised in men than in women. However, there are adverse consequences of PCMD for men, their partners and...
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Thach Duc Tran,
Tuan Tran,
Jane Fisher
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104-109
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Inflammatory markers and their relationships with leptin and insulin from acute mania to full remission in bipolar disorder
Abstract: Background: Weight gain and increased production of leptin may be associated with immuno-modulation and insulin resistance in bipolar disorder. The links among inflammatory markers, leptin, ...
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Shang-Ying Tsai,
Kuo-Hsuan Chung,
Jui-Yu Wu,
Chian-Jue Kuo,
Hsin-Chien Lee,
Shou-Hung Huang
et al.
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110-116
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The impact of the catastrophic earthquake in China's Sichuan province on the mental health of pregnant women
Abstract: Background: On May 12, 2008, a magnitude 8.0 earthquake struck China's southwestern Sichuan province. Recent studies have identified mental health problems among the survivors, but little is...
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Zhiyong Qu,
Donghua Tian,
Qin Zhang,
Xiaohua Wang,
Huan He,
Xiulan Zhang,
Lili Huang,
Fan Xu
et al.
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117-123
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Neural correlates of disbalanced motor control in major depression
Abstract: Background: Motor retardation is a common symptom of major depressive disorder (MDD). Despite the existence of various assessment methods, little is known on the pathobiology of motor retard...
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S. Walther,
O. Höfle,
A. Federspiel,
H. Horn,
S. Hügli,
R. Wiest,
W. Strik,
T.J. Müller
et al.
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124-133
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Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
Abstract: Background: Depression is accompanied by an inflammatory reaction and activation of cell mediated immunity (CMI) and stressors may induce the cytokine network in humans. The proinflammatory ...
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Eva Haastrup,
Jens Drachmann Bukh,
Camilla Bock,
Maj Vinberg,
Lise Wegner Thørner,
Thomas Hansen,
Thomas Werge,
Lars Vedel Kessing,
Henrik Ullum
et al.
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134-138
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| Preliminary Communications |
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Developing a clinical typology of dysfunctional anger
Abstract: Background: This study attempted to validate a clinical typology of dysfunctional anger proposed by DiGiuseppe and Tafrate (2007) using assessment data obtained from 197 participants assesse...
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Adekunle G. Ahmed,
Drew A. Kingston,
Raymond DiGiuseppe,
John M. Bradford,
Michael C. Seto
et al.
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139-148
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Episode cycles with increasing recurrences in first-episode bipolar-I disorder patients
Abstract: Background: Preliminary review of a century of studies of the course of manic-depressive syndromes produced 40 reports, of which approximately one-third report evidence of shortening wellnes...
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R.J. Baldessarini,
P. Salvatore,
H.-M.K. Khalsa,
H. Imaz-Etxeberria,
A. Gonzalez-Pinto,
M. Tohen
et al.
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149-154
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A comparison of three screening tools to identify perinatal depression among low-income African American women
Abstract: Background: The purpose of the current study was to determine the sensitivity, specificity, and positive predictive value of three depression screening tools among a low-income African Ameri...
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S. Darius Tandon,
Fallon Cluxton-Keller,
Julie Leis,
Huynh-Nhu Le,
Deborah F. Perry
et al.
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155-162
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| Brief reports |
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The sustained mood-stabilizing effect of memantine in the management of treatment resistant bipolar disorders: Findings from a 12-month naturalistic trial
Abstract: Background: We have recently provided preliminary clinical observations indicating that memantine, as augmenting agent, was associated with a meaningful antimanic and mood-stabilizing effect...
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Athanasios Koukopoulos,
Giulia Serra,
Alexia E. Koukopoulos,
Daniela Reginaldi,
Gino Serra
et al.
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163-166
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Suicide Intent Scale in the prediction of suicide
Abstract: Objective: To assess the predictive value of the Suicide Intent Scale in patients with high suicide risk. The secondary aim was to assess if the use of the factors of the Suicide Intent Scal...
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J. Stefansson,
P. Nordström,
J. Jokinen
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167-171
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A prospective cohort study of lesion location and its relation to post-stroke depression among Chinese patients
Abstract: Background: Post-stroke depression (PSD) is a common consequence of stroke that negatively interferes with the rehabilitation outcome in patients. It remains unclear what relationship exists...
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Tong Zhang,
Xue Jing,
Xingquan Zhao,
Chunxue Wang,
Zhaorui Liu,
Yong Zhou,
Yilong Wang,
Yongjun Wang
et al.
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e83-e87
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Long-term treatment with supraphysiological doses of thyroid hormone in affective disorders — effects on bone mineral density
Abstract: Background: To investigate the long-term effects of supraphysiological, TSH suppressive doses of levothyroxine (TSDL) on bone mineral density (BMD) in patients with affective disorders durin...
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Roland Ricken,
Felix Bermpohl,
Peter Schlattmann,
Tom Bschor,
Mazda Adli,
Norbert Mönter,
Michael Bauer
et al.
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e89-e94
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A randomized, single-blind, comparison of duloxetine with bupropion in the treatment of SSRI-resistant major depression
Abstract: Introduction: For patients who continue to experience depressive symptoms despite an adequate antidepressant SSRI trial, across-class switch is considered one of the best treatment options. ...
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G. Rosso,
S. Rigardetto,
F. Bogetto,
G. Maina
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172-176
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Molecular cytogenetic interphase analysis of Phosphoinositide-specific Phospholipase C β1 gene in paraffin-embedded brain samples of major depression patients
Abstract: Mood disorders represent a major medical need, as their chronic treatments are not effective in all patients. Literature data suggested that phosphoinositides (PI) signal transduction pathwa...
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Vincenza Rita Lo Vasco,
Patrizia Polonia
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177-180
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Increased plasma VEGF levels in major depressive or manic episodes in patients with mood disorders
Abstract: Background: The neurotrophic hypothesis suggests that mood disorders are associated with dysfunction of neuronal networks under the influence of neurotrophic factors. Vascular endothelial gr...
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Bun-Hee Lee,
Yong-Ku Kim
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181-184
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Protein levels of β-catenin and activation state of glycogen synthase kinase-3β in major depression. A study with postmortem prefrontal cortex
Abstract: Background: The Wnt/GSK3β signaling pathway was implicated in mood disorders. Beta-catenin is a protein targeted by this signaling axis. We aimed to examine whether there is an abnormality i...
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Félicien Karege,
Nader Perroud,
Sandra Burkhardt,
Rafael Fernandez,
Eladia Ballmann,
Romano La Harpe,
Alain Malafosse
et al.
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185-188
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Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression
Abstract: Background: An interaction between recent stressful life events (SLEs) and a serotonin transporter promoter polymorphism (5-HTTLPR) in depression has been inconsistently reported. Some of th...
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Helen L. Fisher,
Sarah Cohen-Woods,
Georgina M. Hosang,
Rudolf Uher,
Georgia Powell-Smith,
Robert Keers,
Maria Tropeano,
Ania Korszun,
Lisa Jones,
Ian Jones,
Mike Owen,
Nick Craddock,
Ian W. Craig,
Anne E. Farmer,
Peter McGuffin
et al.
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189-193
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The railway suicide death of a famous German football player: Impact on the subsequent frequency of railway suicide acts in Germany
Abstract: Background: The railway suicide of Robert Enke, an internationally respected German football goal keeper, sent shockwaves throughout the world of football. We analyzed its impact on the freq...
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Karl-Heinz Ladwig,
Sabine Kunrath,
Karoline Lukaschek,
Jens Baumert
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194-198
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