Journal of Affective Disorders
Volume 60, Issue 1 , Pages 25-32 , October 2000

MRI-based measurements of temporal lobe and ventricular structures in patients with bipolar I and bipolar II disorders

  • Peter Hauser, M.D.

      Affiliations

    • Department of Psychiatry, University of Maryland Medical Center and Psychiatry Service, Baltimore VA Medical Center, 10 North Greene Street, Baltimore, MD 21201, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-410-605-7351; fax: +1-410-605-7918
    • ,
  • John Matochik, Ph.D.

      Affiliations

    • Brain Imaging Center, NIDA, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    • ,
  • Lori L. Altshuler, M.D.

      Affiliations

    • Department of Psychiatry and the Behavioral Sciences, UCLA Neuropsychiatric Hospital, 740 Westwood Blvd. Los Angeles, CA 90266, USA
    • ,
  • Kirk D. Denicoff, M.D.

      Affiliations

    • Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    • ,
  • Andrew Conrad, Ph.D.

      Affiliations

    • Department of Anatomy and Cell Biology, UCLA School of Medicine, Center for Health Sciences, Los Angeles, CA 90024, USA
    • ,
  • Ximing Li, M.D.

      Affiliations

    • Department of Anatomy and Cell Biology, UCLA School of Medicine, Center for Health Sciences, Los Angeles, CA 90024, USA
    • ,
  • Robert M. Post, M.D.

      Affiliations

    • Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA

Received 2 September 1998 ,Accepted 20 August 1999.

References 

  1. Altshuler LL, Conrad A, Hauser P, Li X, Guze BH, Denicoff K, et al. Temporal lobe volume reduction in bipolar disorder: a preliminary MRI report. Arch. Gen. Psychiatry. 1991;48:482–483
  2. Altshuler LL, Curran JG, Hauser P, Mintz J, Conrad A, Denicoff K, et al. T2 hyperintensities in bipolar disorder: MRI comparison and literature meta-analysis. Am. J. Psychiatry. 1995;152:1139–1144
  3. Dunner DL. A review of the diagnostic status of ‘bipolar II’ for the DSM IV work group on mood disorders. Depression. 1993;1:2–10
  4. Elkis H, Friedman L, Wise A, Meltzer HY. Meta-analyses of studies of ventricular enlargement and cortical sulcal prominence in mood disorders. Arch. Gen. Psychiatry. 1995;52:735–746
  5. Fieve RR, Go R, Dunner DL, Elston R. Search for biological/genetic markers in a long term epidemiological and morbid risk study of affective disorders. J. Psychiatric Res. 1984;18:425–445
  6. Harvey I, Persaud R, Ron MA, Baker G, Murray RM. Volumetric MRI measurements in bipolars compared with schizophrenics and healthy controls. Psychol. Med. 1994;24(3):689–699
  7. Hauser P, Altshuler LL, Berrettini W, Dauphinais D, Gelernter J, Post RM. Temporal lobe measurement in primary affective disorder by magnetic resonance imaging. J. Neuropsychiatry Clin. Neurosci. 1989;1:128–134
  8. Hauser P. Magnetic resonance imaging in primary affective disorder. In:  Hauser P editors. Brain Imaging in the Affective Disorders. Washington, DC: American Psychiatric Press; 1991;p. 25–53
  9. Jeste DV, Lohr JB. Neuroanatomical studies of major affective disorders: a review and suggestions for further research. Br. J. Psychiatry. 1988;153:444–459
  10. Johnstone EC, Owens DG, Crow TJ, Frith CD, Alexandropolis K, Bydder G, et al. Temporal lobe structure as determined by nuclear magnetic resonance in schizophrenia and bipolar affective disorder. J. Neurol. Neurosurg. Psychiatry. 1989;52:736–741
  11. Schlegel S. Computed tomography in affective disorders. In:  Hauser P editors. Brain Imaging in the Affective Disorders. Washington, D.C: American Psychiatric Press; 1991;p. 1–24
  12. Spitzer RL, Endicott J, Robins E. Research diagnostic criteria: rationale and reliability. Arch. Gen. Psychiatry. 1978;35:773–782
  13. Swayze VW, Andreasen NC, Alliger W, Ehrhardt JC, Yuh WTC. Structural brain abnormalities in bipolar affective disorder: ventricular enlargement and focal signal hyperintensities. Arch. Gen. Psychiatry. 1990;47:1054–1059
  14. Swayze VW, Andreasen NC, Alliger W, Ehrhardt JC, Yuh WTC. Subcortical and temporal structures in affective disorder and schizophrenia: a magnetic resonance imaging study. Biol. Psychiatry. 1992;31:221–240

PII: S0165-0327(99)00154-8

Journal of Affective Disorders
Volume 60, Issue 1 , Pages 25-32 , October 2000

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