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Journal of Affective Disorders
Volume 122, Issue 1
, Pages 14-26
, April 2010
A genome-wide linkage study of bipolar disorder and co-morbid migraine: Replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11
References
- . Merlin: rapid analysis of dense genetic maps using sparse gene flow trees. Nat. Genet. 2002;30:97–101
- . Depressive disorders: toward a unified hypothesis. Science. 1973;182:20–29
- . Trait components provide tools to dissect the genetic susceptibility of migraine. Am. J. Hum. Genet. 2006;79(1):85–99
- . Consistently replicating locus linked to migraine on 10q22-q23. Am. J. Hum. Genet. 2008;85(5):1051–1063PMID: 18423523 [PubMed - indexed for MEDLINE]
- . Toward a biaxial model of “bipolar” affective disorders: spectrum phenotypes as the products of neuroelectrical and neurochemical alterations. J. Affect. Disord. 2006;94:15–33
- . Genome scan for susceptibility loci for schizophrenia and bipolar disorder. Biol. Psychiatry. 2002;52(1):40–52
- . Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement. Mol. Psychiatry. 2008;13(5):466–467
- . Localization of a gene for migraine without aura to chromosome 4q21. Am. J. Hum. Genet. 2003;73(5):986–993
- . A locus for bipolar affective disorder on chromosome 4p. Nat. Genet. 1996;4:427–430
- . Lamotrigine in the treatment of bipolar disorder. Expert. Opin. Pharmacother. 2002;3(10):1513–1519Review
- . A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group. Arch. Gen. Psychiatry. 2000;57(5):481–489
- . Migraine, physical health and psychiatric disorders: a prospective epidemiologic study in young adults. J. Psychiatr. Res. 1993;27:211–221
- . Significant linkage to migraine with aura on chromosome 11q24. Hum. Mol. Genet. 2003;12(19):2511–2517
- . Identification of a susceptibility locus for migraine with and without aura on 6p12.2–p21.1. Neurology. 2002;59(11):1804–1807
- . Genome-wide scan of bipolar disorder and investigation of population stratification effects on linkage: support for susceptibility loci at 4q21, 7q36, 9p21, 12q24, 14q24, and 16p13. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2007;144B(6):791–801
- . A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. Hum. Mol. Genet. 2001;10(25):2933–2944
- . Genetics of bipolar disorder. J. Med. Genet. 1999;36:585–594
- . Genetics of affective (mood) disorders. Eur. J. Hum. Genet. 2006;14:660–667
- . Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23–q24, and suggests the presence of additional loci on 1p and 1q. Psychiatr. Genet. 2003;13(2):77–84
- . Migraine: Manifestations, Pathogenesis, and Management. New York: Oxford University Press; 2002;
- . Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump α2 subunit associated with familial hemiplegic migraine type 2. Nat. Genet. 2003;33:192–196
- . Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q. Am. J. Med. Genet. 1997;74(3):254–262
- . A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc. Natl. Acad. Sci. USA. 1999;96(10):5604–5609
- . Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet. 2005;366:371–377
- . Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees. Am. J. Med. Genet. 2002;114(4):407–412
- . Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am. J. Hum. Genet. 2003;73(1):107–114
- . Elevated serum levels of C-reactive protein are associated with mania symptoms in outpatients with bipolar disorder. Prog. Neuro-psychopharmacol. Biol. Psychiatry. 2007;31:952–955
- . Is a family history of bipolar disorder a risk factor for migraine?. Psychopathology. 2009;42(2):119–123
- . Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22. Am. J. Med. Genet. 1997;74(3):238–246
- . Bipolar disorder susceptibility region on Xq24–q27.1 in Finnish families. Mol. Psychiatry. 2002;7(5):453–459
- . Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder. Hum. Mol. Genet. 2003;12(15):1907–1915
- . The Na,K-ATPase hypothesis for bipolar illness. Biol. Psychiatry. 1995;37:235–244
- . Intracerebroventricular administration of ouabain as a model of mania in rats. Bipolar. Disord. 2003;5:362–365
- . Dopamine receptors—physiological understanding to therapeutic intervention potential. Pharmacol. Ther. 1999;84:133–156
- . Psychophysiological correlates of “bipolarity”. J. Affect. Disord. 1989;17:47–56
- . Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14. Mol. Psychiatry. 2006;11(7):685–694
- . Support for the possible locus on chromosome 4p16 for bipolar affective disorder. Mol. Psychiatry. 1998;5:442–448
- . A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22–21, 4p16, 6q14–22, 10q26 and 16p13.3. Mol. Psychiatry. 2002;7(7):734–744
- . Genome wide scan using homozygosity mapping and linkage analyses of a single pedigree with affective disorder suggests oligogenic inheritance. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2003;120(1):63–71
- . Genomewide linkage scan for bipolar-disorder susceptibility loci among Ashkenazi Jewish families. Am. J. Hum. Genet. 2004;75(2):204–219
- . The prevalence of migraine in patients with bipolar and unipolar affective disorders. Cephalalgia. 2001;21:894–899
- . Migraine as a cerebral ionopathy with abnormal central sensory processing. In: Gilman S editors. Neurobiology of Disease. New York, NY: Elsevier; 2006;p. 333–348
- . A new locus for hemiplegic migraine maps to chromosome 1q31. Neurology. 1997;49(5):1231–1238
- . The relative role of genetic and environmental factors in migraine without aura. Neurology. 1999;53:995–999
- . A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Sci. U. S. A. 1998;95(26):15531–15536
- . Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11–q14 and 13q21–33. Am. J. Psychiatry. 2007;164(2):236–247
- . Manic-depressive Illness. New York: Oxford University Press; 2007;
- . Serotonin and migraine: biology and clinical implications. Cephalalgia. 2007;27:1295–1300
- . Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch. Gen. Psychiatry. 2005;62(10):1081–1088
- . Pathophysiology of migraine—new insights. Can. J. Neurol. Sci. 1999;26(Suppl 3):S12–S19
- . The International Classification of Headache Disorders, 2nd Ed.. Cephalalgia. 2004;24:1–160
- . Screening for bipolar disorder in the community. J. Clin. Psychiatry. 2003;64:53–59
- . Migraine and concomitant symptoms among 8167 adult twin pairs. Headache. 1995;35:70–78
- . The first genomewide interaction and locus-heterogeneity linkage scan in bipolar affective disorder: strong evidence of epistatic effects between loci on chromosomes 2q and 6q. Am. J. Hum. Genet. 2007;81(5):974–986
- . Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. Genomics. 2001;78(3):150–154
- . Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16. Am. J. Psychiatry. 2007;64(7):1099–1104
- . Role of mitochondrial DNA in calcium signaling abnormality in bipolar disorder. Cell Calcium. 2008;44(1):92–102
- . Mitochondrial dysfunction in bipolar disorder. Bipolar Disord. 2000;2:180–190
- . Linkage and candidate gene analysis of 14q22–24 in bipolar disorder: support for GCHI as a novel susceptibility gene. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2005;136B(1):75–80
- . A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc. Natl. Acad. Sci. USA. 2001;98(2):585–590
- . Evidence of linkage to psychosis on chromosome 5q33–34 in pedigrees ascertained for bipolar disorder. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2007;144B(1):74–78
- . Allele-sharing models: LOD scores and accurate linkage tests. Am. J. Hum. Genet. 1997;61:1179–1188
- . A combined linkage-physical map of the human genome. Am. J. Hum. Genet. 2004;75:1143–1148
- . Molecular cloning of a third member of the potassium-dependent sodium–calcium exchanger gene family, NCKX3. J. Biol. Chem. 2001;276(25):23161–23172
- . Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22. Mol. Psychiatry. 2005;10(9):831–841
- . Lamotrigine reduces migraine aura and migraine attacks in patients with migraine with aura. J. Neurol. Neurosurg. Psychiatry. 2005;76(12):1730–1732
- . Genetic influence in headaches: a Swedish twin study. Headache. 1995;35:513–519
- . A typical migraine susceptibility region localizes to chromosome 1q31. Neurogenetics. 2002;4(1):17–22
- . A genome-wide scan provides evidence for loci influencing a severe heritable form of common migraine. Neurogenetics. 2005;6(2):67–72
- . A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2008;147B(7):1186–1195
- . Assessment of the effect of age at onset on linkage to bipolar disorder: evidence on chromosomes 18p and 21q. Am. J. Hum. Genet. 2005;77(4):545–555
- . Prevalence, clinical correlates, and treatment of migraine in bipolar disorder. Headache. 2003;43:940–949
- . K+-dependent Na+/Ca2+ exchangers in the brain.. Ann. N. Y. Acad. Sci. 2002;976:382–393
- . A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42. Mol. Psychiatry. 2004;12:1083–1090
- . The phenotypes of bipolar disorder: relevance for genetic investigations. Mol. Psychiatry. 2005;10:811–826
- . Serotonin and bipolar disorder. J. Affect. Disord. 2001;66:1–11
- . Prevalence of migraine in bipolar disorder. J. Affect. Disord. 1999;52:239–241
- . A genome-wide linkage search for bipolar disorder susceptibility loci in a large and complex pedigree from the eastern part of Cuba. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2006;141B(8):833–843
- . Migraine prophylaxis with divalproex. Arch. Neurol. 1995;52:281–286
- . Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biol. Psychiatry. 2003;54(11):1265–1273
- . The prevalence and impact of migraine headache in bipolar disorder: results from the Canadian Community Health Survey. Headache. 2006;46(6):973–982
- . Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am. J. Hum. Genet. 2005;77(4):582–595
- . Cyclical migraine. Arch. Neurol. 1981;38:343–344
- . Migraine and psychopathology. Arch. Gen. Psychiatry. 1990;47:849–853
- . Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22. Am. J. Hum. Genet. 2004;74(5):886–897
- . Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in quebec points to a locus of major effect on chromosome 12q23–q24. Am. J. Med. Genet. 1999;88(5):567–587
- . Deciphering migraine mechanisms: clues from familial hemiplegic migraine genotypes. Ann. Neurol. 2004;55:276–280
- . Evidence of linkage and association on 18p11.2 for psychosis. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2006;141B(8):868–873
- . Large-scale integration of human genetic and physical maps. Genome. Res. 2004;14:1199–1205
- . Diagnostic interview for genetic studies: rationale, unique features, and training. Arch. Gen. Psychiat. 1994;51:849–859
- . Evidence for an X-linked genetic component in familial typical migraine. Hum. Mol. Genet. 1998;7(3):459–463
- . Familial typical migraine: linkage to chromosome 19p13 and evidence for genetic heterogeneity. Neurology. 1998;50(5):1428–1432
- . Familial typical migraine: significant linkage and localization of a gene to Xq24–28. Hum. Genet. 2000;107(1):18–23
- . Genomewide significant linkage to migrainous headache on chromosome 5q21. Am. J. Hum. Genet. 2005;77(3):500–512
- . Is migraine in unipolar depressed patients a bipolar spectrum trait?. J. Affect. Disord. 2005;84:233–242
- . Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell. 1996;87:543–552
- . Evidence of a predisposing locus to bipolar disorder on Xq24–q27.1 in an extended Finnish pedigree. Genome Res. 1995;5(2):105–115
- . Dopamine and migraine. Neurology. 1997;49:650–656
- . Familial hemiplegic migraine. Neurotherapeutics. 2007;4:274–284
- . Scanning the genome with 1772 microsatellite markers in search of a bipolar disorder susceptibility gene. Mol. Psychiatry. 1996;1(5):404–407PMID: 9154235 [PubMed - indexed for MEDLINE]
- . An apparently dominant bipolar affective disorder (BPAD) locus on chromosome 20p11.2–q11.2 in a large Turkish pedigree. Eur. J. Hum. Genet. 2001;(1):39–44
- . Alpha2 isoform of the Na,K-adenosine triphosphatase is reduced in temporal cortex of bipolar individuals. Biol. Psychiatry. 1998;44:892–897
- . A new susceptibility locus for migraine with aura in the 15q11–q13 genomic region containing three GABA-A receptor genes. Am. J. Hum. Genet. 2005;76(2):327–333
- . Preliminary evidence for linkage to chromosome 1q31–32, 10q23.3, and 16p13.3 in a South African cohort with bipolar disorder. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2007;144B(3):383–387
- . Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35–p36 and provides further evidence of loci on chromosome 4q31 and 6q24. Am. J. Hum. Genet. 2005;77(6):1102–1111
- . Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: bipolar disorder. Am. J. Hum. Genet. 2003;73:49–62
- . Serotonin (5-HT) and migraine. Headache. 1994;34:408–417
- . Divalproex sodium in headache: literature review and clinical guidelines. Headache. 1996;36:547–555
- . Migraine pathophysiology and its clinical implications. Cephalalgia. 2004;24(Suppl 2):2–7
- . Migraine: preventive treatment. Cephalalgia. 2002;22:491–512
- . Whole-genome association study of bipolar disorder. Mol. Psychiatry. 2008;13(6):558–569
- . Family, twin, and adoption studies of bipolar disorder. Am. J. Med. Genet. 2003;60:497–502
- . A locus for migraine without aura maps on chromosome 14q21.2–q22.3. Am. J. Hum. Genet. 2003;72(1):161–167
- . Genetic linkage study for bipolar disorders on chromosomes 17 and 18 in families with a high expression of mental illness from the Balearic Islands.. Psychiatr. Genet. 2006;16(4):145–151
- . Type I bipolar disorder associated with a fragile site on chromosome 1. Am. J. Med. Genet. 1995;60(3):179–182
- . Platelet glutamate uptake and release in migraine with and without aura. Cephalalgia. 2007;27(1):35–40
- . Genetic models of migraine. Arch. Neurol. 2007;64(5):643–646
- . Increased C-reactive protein in young adult patients with migraine. Cephalalgia. 2007;27:843–846
- . Mitochondria, magnesium and migraine. J. Neurol. Sci. 1995;4(1–2):9–14Review
- . A susceptibility locus for migraine with aura, on chromosome 4q24. Am. J. Hum. Genet. 2002;70(3):652–662
- . Migraine: a complex genetic disorder. Lancet Neurol. 2007;6:521–532
- . Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21.. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2003;121B(1):21–27
- . World Health Report. 2002;
- . Genome-wide linkage scan of 98 bipolar pedigrees and analysis of clinical covariates. Mol. Psychiatry. 2007;12(7):630–639
☆ NIMH Genetics Initiative for Bipolar Disorder Consortium authors include: J. Nurnberger, Indiana University; W. Byerley, University of California, San Francisco; J. Kelsoe, University of California, San Diego; M. McInnis, University of Michigan; J. Potash, Johns Hopkins; E. Gershon, University of Chicago; W. Scheftner, Rush University Medical Center; W. Coryell, University of Iowa; W. Berrettini, University of Pennsylvania; F. McMahon, National Institute of Mental Health; J. Rice, Washington University.
PII: S0165-0327(09)00273-0
doi: 10.1016/j.jad.2009.06.014
© 2009 Elsevier B.V. All rights reserved.
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Journal of Affective Disorders
Volume 122, Issue 1
, Pages 14-26
, April 2010
