Journal of Affective Disorders
Volume 122, Issue 1 , Pages 60-67 , April 2010

Randomized comparison of ultra-brief bifrontal and unilateral electroconvulsive therapy for major depression: cognitive side-effects

  • P. Sienaert

      Affiliations

    • ECT Department, University Psychiatric Center, Catholic University of Leuven, campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    • Department of Mood Disorders, University Psychiatric Center, Catholic University of Leuven, campus Kortenberg, Leuvensesteenweg 517, 3070, Kortenberg, Belgium
    • Corresponding Author InformationCorresponding author. University Psychiatric Center, Catholic University of Leuven, campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium. Tel.: +32 2 758 5 11; fax: +32 2 759 53 80.
  • ,
  • K. Vansteelandt

      Affiliations

    • University Psychiatric Center, Catholic University of Leuven, campus Kortenberg, Kortenberg, Belgium
  • ,
  • K. Demyttenaere

      Affiliations

    • University Psychiatric Center, Catholic University of Leuven, campus Leuven, Leuven, Belgium
  • ,
  • J. Peuskens

      Affiliations

    • University Psychiatric Center, Catholic University of Leuven, campus Kortenberg, Kortenberg, Belgium

Received 21 February 2009 ,Revised 10 June 2009 ,Accepted 11 June 2009.

References 

  1. Airaksinen E, Larsson M, Lundberg I, Forsell Y. Cognitive functions in depressive disorders: evidence from a population-based study. Psychol. Med. 2004;34:83–91
  2. Austin MP, Mitchell P, Wilhelm K, Parker G, Hickie I, Brodaty H. Cognitive function in depression: a distinct pattern of frontal impairment in melancholia?. Psychol. Med. 1999;29:73–85
  3. Castaneda AE, Suvisaari J, Marttunen M, Perala J, Saarni SI, alto-Setala T. Cognitive functioning in a population-based sample of young adults with a history of non-psychotic unipolar depressive disorders without psychiatric comorbidity. J. Affect. Disord. 2008;110:36–45
  4. Coffey CE. Some brief thoughts on ultra-brief pulse ECT. Brain Stimul. 2008;1:86–87
  5. Cronholm B, Ottosson J-O. Ultrabrief stimulus technique in electroconvulsive therapy. I. Influence on retrograde amnesia of treatments with the Elther ES electroshock apparatus, Siemens Konvulsator III and of lidocaine-modified treatment. J. Nerv. Ment. Dis. 1963;137:117–123
  6. Cronholm B, Ottosson J-O. Ultrabrief stimulus technique in electroconvulsive therapy. II. Comparative studies of therapeutic effects and memory disturbances in treatment of endogenous depression with the Elther ES electroshock apparatus and Siemens Konvulsator III. J. Nerv. Ment. Dis. 1963;137:268–276
  7. Crowley K, Pickle J, Dale R, Fattal O. A critical examination of bifrontal electroconvulsive therapy: clinical efficacy, cognitive side-effects, and directions for future research. J. ECT. 2008;24:268–271
  8. D'Elia G. Unilateral electroconvulsive therapy. Acta Psychiatr. Scand. Suppl. 1970;215:1–98
  9. Fink M. Complaints of loss of personal memories after electroconvulsive therapy: evidence of a somatoform disorder?. Psychosomatics. 2007;48:290–293
  10. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 1975;12:189–198
  11. Fraser LM, O'Carroll RE, Ebmeier KP. The effect of electroconvulsive therapy on autobiographical memory: a systematic review. J. ECT. 2008;24:10–17
  12. Gueorguieva R, Krystal JH. Move over ANOVA: progress in analyzing repeated-measures data and its reflection in papers published in the Archives of General Psychiatry. Arch. Gen. Psychiatry. 2004;61:310–317
  13. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 1960;23:56–62
  14. Ingram A, Saling MM, Schweitzer I. Cognitive side-effects of brief pulse electroconvulsive therapy: a review. J. ECT. 2008;24:3–9
  15. Kellner CH. Ultrabrief pulse right unilateral ECT: should it be the new standard of care?. Psychiatr. Times. 2009;26:
  16. Kim SW, Grant JE, Rittberg BR, Simon JE, Vine CJ, Schulz SC. Decreased memory loss associated with right unilateral ultra-brief pulse wave ECT. Minnesota Med. 2007;90:34–35
  17. Kopelman MD, Wilson BA, Baddeley AD. The autobiographical memory interview: a new assessment of autobiographical and personal semantic memory in amnesic patients. J. Clin. Exp. Neuropsychol. 1989;11:724–744
  18. Lerer B, Isserles M. From Meduna to ultrabrief: new directions for the oldest brain stimulation therapy. Brain Stimul. 2008;1:84–85
  19. Letemendia FJ, Delva NJ, Rodenburg M, Lawson JS, Inglis J, Waldron JJ. Therapeutic advantage of bifrontal electrode placement in ECT. Psychol. Med. 1993;23:349–360
  20. Lisanby SH, Maddox JH, Prudic J, Devanand DP, Sackeim HA. The effects of electroconvulsive therapy on memory of autobiographical and public events. Arch. Gen. Psychiatry. 2000;57:581–590
  21. Loo CK. Cognitive outcomes in electroconvulsive therapy: optimizing current clinical practice and researching future strategies. J. ECT. 2008;24:1–2
  22. Loo CK, Schweitzer I, Pratt C. Recent advances in optimizing electroconvulsive therapy. Aust. N. Z. J. Psychiatry. 2006;40:632–638
  23. Loo C, Sheehan P, Pigot M, Lyndon W. A report on mood and cognitive outcomes with right unilateral ultra-brief pulsewidth (0.3 ms) ECT and retrospective comparison with standard pulsewidth right unilateral ECT. J. Affect. Disord. 2007;103:277–281
  24. Marvel CL, Paradiso S. Cognitive and neurological impairment in mood disorders. Psychiatr. Clin. North Am. 2004;27:19–36
  25. McIntyre C. Brief thoughts on ECT parameter settings. Brain Stimul. 2008;1:88
  26. Pisvejc J, Hyrman V, Sikora J, Berankova A, Kobeda B, Auerova M. A comparison of brief and ultra-brief pulse stimuli in unilateral ECT. J ECT. 1998;14:68–75
  27. Porter RJ, Gallagher P, Thompson JM, Young AH. Neurocognitive impairment in drug-free patients with major depressive disorder. Br. J. Psychiatry. 2003;182:220
  28. Porter R, Heenan H, Reeves J. Early effects of electroconvulsive therapy on cognitive function. J ECT. 2008;24:35–39
  29. Prudic J. Strategies to minimize cognitive side-effects with ECT: aspects of ECT technique. J ECT. 2008;24:46–51
  30. Prudic J, Peyser S, Sackeim HA. Subjective memory complaints: a review of patient self-assessment of memory after electroconvulsive therapy. J ECT. 2000;16:121–132
  31. Rey A. L'examen clinique en psychologie. Paris: Presses Universitaries de France; 1964;
  32. Robertson H, Pryor R. Memory and cognitive effects of ECT: informing and assessing patients. Adv. Psychiatr. Treat. 2006;12:228–237
  33. Robin A, De Tissera S. A double-blind controlled comparison of the therapeutic effects of low and high energy electroconvulsive therapies. Br. J. Psychiatry. 1982;141:357–366
  34. Rose D, Fleischmann P, Wykes T, Leese M, Bindman J. Patients' perspectives on electroconvulsive therapy: systematic review. BMJ. 2003;326:1363–1368
  35. Rosveld HE, Mirsky AF, Sarason I, Bransome ED, Beck LH. A continuous performance test of brain damage. J. Consult. Psychol. 1956;20:343–350
  36. Sackeim HA. Convulsant and anticonvulsant properties of electroconvulsive therapy: towards a focal form of brain stimulation. Clin. Neurosci. Res. 2004;4:39–57
  37. Sackeim HA, Prudic J, Devanand DP, Kiersky JE, Fitzsimons L, Moody BJ. Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy. N. Engl. J. Med. 1993;328:839–846
  38. Sackeim HA, Prudic J, Devanand DP, Nobler MS, Lisanby SH, Peyser S. A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities. Arch. Gen. Psychiatry. 2000;57:425–434
  39. Sackeim HA, Prudic J, Nobler MS, Lisanby SH, Devanand DP, Peyser S. Ultra-brief pulse ECT and the affective and cognitive consequences of ECT. J ECT. 2001;17:77
  40. Sackeim HA, Prudic J, Fuller R, Keilp J, Lavori PW, Olfson M. The cognitive effects of electroconvulsive therapy in community settings. Neuropsychopharmacologia. 2007;32:244–254
  41. Sackeim HA, Prudic J, Nobler MS, Fitzsimons L, Lisanby SH, Payne N. Effects of pulse width and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy. Brain Stimul. 2008;1:71–83
  42. Schat A, van den Broek WW, Mulder PG, Birkenhager TK, van TR, Murre JM. Changes in everyday and semantic memory function after electroconvulsive therapy for unipolar depression. J. ECT. 2007;23:153–157
  43. Sienaert P, Vansteelandt K, Demyttenaere K, Peuskens J. Randomized comparison of ultra-brief bifrontal and unilateral electroconvulsive therapy for major depression: clinical efficacy. J. Affect. Disord. 2009;116:106–112
  44. Sienaert P, Vansteelandt K, Demyttenaere K, Peuskens J. Patient satisfaction after ultra-brief bifrontal and unilateral electroconvulsive therapy for major depression. J. ECT. 2009;
  45. Sobin C, Sackeim HA, Prudic J, Devanand DP, Moody BJ, McElhiney MC. Predictors of retrograde amnesia following ECT. Am. J. Psychiatry. 1995;152:995–1001
  46. Spreen O, Strauss EA. Compendium of Neuropsychological Tests. 2 ed.. New York: Oxford University Press; 1998;
  47. Squire LR, Slater PC. Electroconvulsive therapy and complaints of memory dysfunction: a prospective three-year follow-up study. Br. J. Psychiatry. 1983;142:1–8
  48. Squire LR, Wetzel CD, Slater PC. Memory complaint after electroconvulsive therapy: assessment with a new self-rating instrument. Biol. Psychiatry. 1979;14:791–801
  49. UK ECT Review Group. Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. Lancet. 2003;361:799–808
  50. Valentine M, Keddie K, Dunne D. A comparison of techniques in electroconvulsive therapy. Br. J. Psychiatry. 1964;114:989–996
  51. Wechsler D. Wais-III administration and scoring manual. 4th edition. Amsterdam: Harcourt Test Publishers.; 2004;Dutch version
  52. Williams JM. The prediction of premorbid memory ability. Arch. Clin. Neuropsychol. 1997;12:745–756
  53. Wolfinger RD. Covariance structure selection in general mixed models. Commun. Stat., Simul. Comput. 1993;22:1079–1106
  54. Wolfinger RD. An example of using mixed models and PROC MIXED for longitudinal data. J. Biopharm. Stat. 1997;7:381–500
  55. Wolfinger RD, Chang M. Comparing the SAS GLM and MIXED procedures for repeated measures. Cary, NC: SAS Institute Inc.; 1998;

PII: S0165-0327(09)00271-7

doi: 10.1016/j.jad.2009.06.011

Journal of Affective Disorders
Volume 122, Issue 1 , Pages 60-67 , April 2010