Journal of Affective Disorders
Volume 87, Issue 1 , Pages 83-89 , July 2005

High harm avoidance and low self-directedness in euthymic young adults with recurrent, early-onset depression

  • Daniel J. Smith

      Affiliations

    • Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 131 537 6526; fax: +44 131 447 6860.
  • ,
  • Laura Duffy

      Affiliations

    • Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK
  • ,
  • Mary E. Stewart

      Affiliations

    • Applied Psychology, School of Life Sciences, Heriot-Watt University, Edinburgh, EH14 4AS, UK
  • ,
  • Walter J. Muir

      Affiliations

    • Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK
  • ,
  • Douglas H.R. Blackwood

      Affiliations

    • Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK

Received 30 June 2004 ,Revised 15 March 2005 ,Accepted 15 March 2005.

References 

  1. Abrams KY, Yune SK, Kim SJ, Jeon HJ, Han SO, Hwang J, et al. Trait and state aspects of harm avoidance and its implication for treatment in major depressive disorder, dysthymic disorder, and depressive personality disorder. Psychiatry Clin. Neurosci. 2004;58(3):240–248
  2. Akiskal HS, Hantouche E-G, Allilaire J-F, Sechter D, Bourgeois ML, Azorin J-M, et al. Validating antidepressant-associated hypomania (bipolar III): a systematic comparison with spontaneous hypomania (bipolar II). J. Affect. Disord. 2003;73:65–74
  3. Bagby RM, Joffe RT, et al. Major depression and the five-factor model of personality. J. Pers. Disord. 1995;9:224–234
  4. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry. 1961;4:561–571
  5. Bellivier F, Golmard J-L, Rietschel M, Schulze TG, Malafosse A, Preisig M, et al. Age at onset in bipolar I affective disorder: further evidence for three subgroups. Am. J. Psychiatry. 2003;160(5):999–1001
  6. Brody AL, Saxena S, Fairbanks LA, Alborzian S, Demaree HA, Maidment KM, et al. Personality changes in adult subjects with major depressive disorders or obsessive-compulsive disorder treated with paroxetine. J. Clin. Psychiatry. 2000;61:349–355
  7. Brown SL, Svrakic DM, Przybeck TR, Cloninger CR. The relationship of personality to mood and anxiety states: a dimensional approach. J. Psychiatr. Res. 1992;26:197–211
  8. Cloninger CR. A systematic method for the clinical description and classification of personality variants. Arch. Gen. Psychiatry. 1987;44:573–588
  9. Cloninger CR, Svrakic DM, Przybek TR. A psychobiological model of temperament and character. Arch. Gen. Psychiatry. 1993;50:975–989
  10. Enns MW, Cox BJ. Personality dimensions and depression: review and commentary. Can. J. Psychiatry. 1997;42(3):274–284
  11. Farmer A, Redman K, Harris T, Mahmood A, Sadler S, Pickering A, et al. Neuroticism, extraversion, life events and depression. Br. J. Psychiatry. 2002;181:118–122
  12. Farmer A, Mahmood A, Redman K, Harris T, Sadler S, McGuffin P. A sib-pair study of the Temperament and Character Inventory scales in major depression. Arch. Gen. Psychiatry. 2003;60(5):490–496
  13. First M, Gibbon M, Spitzer RL, Williams JBW. User's Guide for the Structured Clinical Interview for DSM-IV Axis I Disorders-Research Version (SCID-I, Version 2.0, February 1996 FINAL Version). New York: Biometric Research; 1996;
  14. Ghaemi SN, Ko JY, Goodwin FK. Cade's Disease and beyond: misdiagnosis, antidepressant use and a proposed definition for bipolar spectrum disorder. Can. J. Psychiatry. 2002;47(2):125–134
  15. Gillespie NA, Cloninger CR, Heath AC, Martin A. The genetic and environmental relationship between Cloninger's dimensions of temperament and character. Pers. Individ. Differ. 2003;35:1931–1946
  16. Hansenne M, Reggers J, Pinto E, Kjiri K, Ajamier A, Ansseau M. Temperament and Character Inventory (TCI) and depression. J. Psychiatr. Res. 1999;33:31–36
  17. Hirano S, Sato T, Narita T, Kusunoki K, Ozaki N, Kimura S, et al. Evaluating the state dependancy of the Temperament and Character Inventory Dimensions in patients with major depression: a methodological contribution. J. Affect. Disord. 2002;69:31–38
  18. Joffe RT, Bagby RM, Levitt AJ, Regan JJ, Parker JDA. The Tridimensional Personality Questionnaire in major depression. Am. J. Psychiatry. 1993;150:959–960
  19. Katz R, McGuffin P. Neuroticism in familial depression. Psychol. Med. 1987;17:155–161
  20. Kusunoki K, Sato T, Taga C, Yoshida T, Komori K, Narita T, et al. Low novelty-seeking differentiates obsessive-compulsive disorders from major depression. Acta Psychiatr. Scand. 2000;101:403–405
  21. Maher B, Marazita ML, Zubenko WN, Spiker DG, Giles DE, Kaplan BB, et al. Genetic segregation analysis of recurrent, early-onset depression: evidence for single major locus transmission. Am. J. Med. Genet. 2002;114:214–221
  22. Marijnissena G, Tuiniera S, Sijbena AES, Verhoeven WMA. The temperament and character inventory in major depression. J. Affect. Disord. 2002;70(2):219–223
  23. Richter J, Eisemann M, Richter G. Temperament and character during the course of unipolar depression among patients. Eur. Arch. Psychiatr. Clin. Neurosci. 2000;250:40–47
  24. Roberts SB, Kendler KS. Neuroticism and self-esteem as indices of the vulnerability to major depression in women. Psychol. Med. 1999;29:1101–1109
  25. Sher KJ, Bartholow BD, Wood MD. Personality and substance use disorders: a prospective study. J. Consult. Clin. Psychol. 2000;68(5):818–829
  26. Smith DJ, Harrison N, Muir W, Blackwood DHR. The high prevalence of bipolar spectrum disorders in young adults with recurrent depression: toward an innovative diagnostic framework. J. Affect. Disord. 2005;84(2–3):167–178
  27. Zubenko G, Zubenko WN, Spiker DG, Giles DE, Kaplan BB. Malignancy of recurrent, early-onset depression: a family study. Am. J. Med. Genet. 2001;105:690–699
  28. Zuckerman M, Cloninger CR. Relationships between Cloninger's, Zuckerman's, and Eysenck's dimensions of personality. Pers. Individ. Differ. 1996;21(2):283–285

PII: S0165-0327(05)00089-3

doi: 10.1016/j.jad.2005.03.014

Journal of Affective Disorders
Volume 87, Issue 1 , Pages 83-89 , July 2005