Serum lipid profiles in major depression with clinical subtypes, suicide attempts and episodes

Huang, Tiao-Lai

doi:10.1016/j.jad.2004.11.005

Next »Journal of Affective Disorders
Volume 86, Issue 1 , Pages 75-79, May 2005

Serum lipid profiles in major depression with clinical subtypes, suicide attempts and episodes

Department of Psychiatry, Chang Gung Memorial Hospital, 123, Ta-Pei Rd, Niao-Sung, Kaohsiung 833, Taiwan, ROC

Received 9 August 2004; received in revised form 19 November 2004; accepted 19 November 2004.

Abstract

Background

We tried to report the data between serum lipid profiles and major depression with different clinical subtypes, with or without suicide attempts, and with single episode or recurrent episodes.

Method

During a 2-year period, a total of 168 participants (109 patients with major depression and 59 subjects in a healthy control group) were recruited in this study. Blood samples for serum lipid profiles in all participants were collected. Data analysis was performed by using an analysis of covariance (ANCOVA) with body mass index (BMI) adjustment.

Results

The data showed that there were no significant differences of any kind in serum lipid profiles between depressive patients with melancholic feature or atypical feature, with or without suicide attempts nor between depressive patients with single episode or recurrent episodes.

Conclusion

The results suggested there were no serum lipid profiles used as biological markers to distinguish the clinical subtypes, suicide attempts and episodes in patients with major depression.

Keywords: Depression, Cholesterol, Triglyceride, Suicide, Melancholia, Lipid