Journal of Affective Disorders
Volume 81, Issue 1 , Pages 61-66 , July 2004

Measuring depression outcome with a brief self-report instrument: sensitivity to change of the Patient Health Questionnaire (PHQ-9)

  • Bernd Löwe

      Affiliations

    • Corresponding Author InformationCorresponding author. Regenstrief Institute for Health Care, RG-6, Indiana University School of Medicine, 1050 Wishard Boulevard, Indianapolis, IN 46202, USA. Tel.: +1-317-630-7447; fax: +1-317-630-6611.
    • Department of General Internal and Psychosomatic Medicine, University of Heidelberg, Medical Hospital, D-69115 Heidelberg, Germany
    • Regenstrief Institute and Indiana University School of Medicine, Indianapolis, IN 46202, USA
    • ,
  • Kurt Kroenke

      Affiliations

    • Regenstrief Institute and Indiana University School of Medicine, Indianapolis, IN 46202, USA
    • ,
  • Wolfgang Herzog

      Affiliations

    • Department of General Internal and Psychosomatic Medicine, University of Heidelberg, Medical Hospital, D-69115 Heidelberg, Germany
    • ,
  • Kerstin Gräfe

      Affiliations

    • Department of General Internal and Psychosomatic Medicine, University of Heidelberg, Medical Hospital, D-69115 Heidelberg, Germany

Received 1 May 2003 ,Revised 17 July 2003 ,Accepted 17 July 2003.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Text Revision. Washington, DC: American Psychiatric Association; 2000;
  2. Aneshensel CS, Frerichs RR, Clark VA, Yokopenic PA. Measuring depression in the community: a comparison of telephone and personal interviews. Public Opin. Q. 1982;46:110–121
  3. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed.. Hillsdale: Erlbaum; 1988;
  4. Deyo RA, Diehr P, Patrick DL. Reproducibility and responsiveness of health status measures. Statistics and strategies for evaluation. Control Clin. Trials. 1991;12:142S–158S
  5. First MB, Spitzer RL, Williams JBW, Gibbon M. Structured Clinical Interview for DSM-IV (SCID). Washington, DC: American Psychiatric Association; 1995;
  6. Guyatt G, Walter S, Norman G. Measuring change over time: assessing the usefulness of evaluative instruments. J. Chronic. Dis. 1987;40:171–178
  7. Hamilton D. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 1960;23:56–62
  8. Hevey D, McGee HM. The effect size statistic. Useful in health outcomes research?. J. Health Psychol. 1998;3:163–170
  9. Kazis LE, Anderson JJ, Meenan RF. Effect sizes for interpreting changes in health status. Med. Care. 1989;27:S178–S189
  10. Kobak KA, Taylor LH, Dottl SL, Greist JH, Jefferson JW, Burroughs D, et al. A computer-administered telephone interview to identify mental disorders. JAMA. 1997;278:905–910
  11. Kroenke K, Spitzer RL, Williams JB. The PHQ-9. Validity of a brief depression severity measure. J. Gen. Intern. Med. 2001;16:606–613
  12. Liang MH, Fossel AH, Larson MG. Comparisons of five health status instruments for orthopedic evaluation. Med. Care. 1990;28:632–642
  13. Löwe, B., Spitzer, R.L., Gräfe, K., Kroenke, K., Quenter, A., Zipfel, S., Buchholz, C., Witte, S., Herzog, W., in press, a. Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians' diagnoses. J. Affect. Disord.
  14. Löwe, B., Gräfe, K., Zipfel, S., Spitzer, R.L., Hermann-Lingen, C., Witte, S., Herzog, W., in press, b. Detecting Panic Disorder in Medical and Psychosomatic Outpatients: Comparative validation of the Hospital Anxiety and Depression Scale, the Patient Health Questionnaire, a Screening Question, and Physicians' Diagnosis. J. Psychosom. Res.
  15. Löwe B, Spitzer RL, Zipfel S, Herzog W. Gesundheitsfragebogen für Patienten (PHQ-D). Manual und Testunterlagen. 2. Auflage ([PRIME MD Patient Health Questionnaire (PHQ) - German version. Manual and materials, 2nd Edition]), Karlsruhe: Pfizer; 2002;
  16. Schuck P. Designs und Kennziffern zur Ermittlung der Änderungssensitivität von Fragebogen in der gesundheitsbezogenen Lebensqualitätsforschung ([Designs and statistics for assessing responsiveness of questionnaires in health-related quality of life research]), Z. Med. Psychol. 2000;9:125–130
  17. Simon GE, Revicki D, VonKorff M. Telephone assessment of depression severity. J. Psychiatr. Res. 1993;27:247–252
  18. Spitzer RL, Kroenke K, Williams JB, Patient Health Questionnaire Primary Care Study Group . Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. JAMA. 1999;282:1737–1744
  19. Wells KB, Burnam MA, Leake B, Robins LN. Agreement between face-to-face and telephone-administered versions of the depression section of the NIMH Diagnostic Interview Schedule. J. Psychiatr. Res. 1988;22:207–220

PII: S0165-0327(03)00198-8

doi: 10.1016/S0165-0327(03)00198-8

Journal of Affective Disorders
Volume 81, Issue 1 , Pages 61-66 , July 2004

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