Journal of Affective Disorders
Volume 81, Issue 2 , Pages 173-178 , August 2004

Modafinil treatment in patients with seasonal affective disorder/winter depression: an open-label pilot study

  • Leslie Lundt

      Affiliations

    • Corresponding Author InformationTel.: +1-208-429-1627; fax: +1-208-344-2104.

Received 7 February 2003 ,Accepted 21 April 2003.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders, DSM-IV™. 4th Edition. Washington, DC: American Psychiatric Association; 1994;
  2. DeBattista C., Solvason H.B., Kendrick E., Schatzberg A.F., 2001. Modafinil as an adjunctive agent in the treatment of fatigue and hypersomnia associated with major depression. Presented at the Annual Meeting of American Psychiatric Association, New Orleans, LA.
  3. DeBattista C., Doghramji K., Menza M.A., Rosenthal M.H., Fieve, R., 2003. J. Clin. Psychiatry, in press.
  4. Guy W. ECDEU Assessment Manual for Psychopharmacology. Revised. Rockville, MD: US National Institute of Health, Psychopharmacology Research Branch; 1976;
  5. Hilger E, Willeit N, Praschk-Rieder N, Stastny A, Neumeister A, Kasper S. Reboxetine in seasonal affective disorder: an open trial. Eur. Neuropsychophamacol. 2001;11:1–5
  6. Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep. 1991;14:540–545
  7. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Applications to patients with multiple sclerosis and systemic lupus erythematosus. Arch. Neurol. 1989;46:1121–1123
  8. Lam RW, Gorman CP, Michalon M, Steiner M, Levitt AJ, Corral MR, et al. Multicenter, placebo-controlled study of fluoxetine in seasonal affective disorder. Am. J. Psychiatry. 1995;152:1765–1770
  9. Magnusson A. An overview of epidemiological studies on seasonal affective disorder. Acta Psychiatr. Scand. 2000;101:176–184
  10. Menza MA, Kaufman KR, Castellanos A. Modafinil augmentation of antidepressant treatment in depression. J. Clin. Psychiatry. 2000;61:378–381
  11. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br. J. Psychiatry. 1979;134:382–389
  12. Partonen T, Lonnqvist J. Seasonal affective disorder. Lancet. 1998;352:1369–1374
  13. Partonen T, Lonnqvist J. Moclobemide and fluoxetine in treatment of seasonal affective disorder. J. Affect. Disord. 1996;41:93–99
  14. Rosenthal NE, Sack DA, Gillin JC, Lewy AJ, Goodwin FK, Davenport Y, et al. Seasonal affective disorder: a description of the syndrome and preliminary findings with light therapy. Arch. Gen. Psychiatry. 1984;41:72–80
  15. Ruhrmann S, Kaspar S, Hawellek B, Martinez B, Hoflich G, Nickelsen Y, et al. Effects of fluoxetine versus bright light in the treatment of seasonal affective disorder. Psychol. Med. 1998;28:923–933
  16. Scammell TE, Estabrooke IV, McCarthy MT, Chemelli RM, Yanagisawa M, Miller MS, et al. Hypothalamic arousal regions are activated during modafinil-induced wakefulness. J. Neurosci. 2000;20:8620–8628
  17. Terman M, Terman JS. Bright light therapy: side effects and benefits across the symptom spectrum. J. Clin. Psychiatry. 1999;60:799–808
  18. US Modafinil in Narcolepsy Multicenter Study Group . Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy. Neurology. 2000;54:1166–1175
  19. Williams JBW, Link MJ, Rosenthal NE, Amira L, Terman M. Structured Interview Guide for the Hamilton Depression Rating Scale-Seasonal Affective Disorder Version (SIGH-SAD). Revised Edition. New York: New York State Psychiatric Institute; 1994;

PII: S0165-0327(03)00162-9

doi: 10.1016/S0165-0327(03)00162-9

Journal of Affective Disorders
Volume 81, Issue 2 , Pages 173-178 , August 2004

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