Journal of Affective Disorders
Volume 81, Issue 2 , Pages 167-171 , August 2004

Sensitivity and specificity of the Mood Disorder Questionnaire for detecting bipolar disorder

  • Christopher J Miller

      Affiliations

    • Bipolar Disorder Research Program, Cambridge Hospital, Cambridge, MA, USA
    • Consolidated Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    • ,
  • Jeffry Klugman

      Affiliations

    • Atlantic Health Services, New Haven, CT, USA
    • Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    • ,
  • Douglas A Berv

      Affiliations

    • Atlantic Health Services, New Haven, CT, USA
    • Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    • ,
  • Klara J Rosenquist

      Affiliations

    • Bipolar Disorder Research Program, Cambridge Hospital, Cambridge, MA, USA
    • Consolidated Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    • ,
  • S Nassir Ghaemi

      Affiliations

    • Bipolar Disorder Research Program, Cambridge Hospital, Cambridge, MA, USA
    • Consolidated Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, The Cambridge Hospital, 1493 Cambridge St., Cambridge, MA 02139, USA. Tel.: +1-617-665-1612; fax: +1-617-665-1623.

Received 23 August 2002 ,Accepted 3 June 2003.

References 

  1. Akiskal HS. Classification, diagnosis, and boundaries of bipolar disorders: a review. In:  Maj M,  Akiskal HS,  Lopez-Ibor JJ,  Sarotius N editor. Bipolar Disorder. Chichester: Wiley; 2002;p. 1–52
  2. Akiskal HS, Bourgeois ML, Angst J, Post R, Moller HJ, Hirschfeld R. Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders. J. Affect. Disord. 2000;59:S5–S30
  3. Akiskal HS, Pinto O. The evolving bipolar spectrum: prototypes I, II, III, and IV. Psychiatr. Clin. North. Am. 1999;22:517–534
  4. Amador XA, Strauss DH, Yale SA, Flaum MM, Endicott J, Gorman JM. Assessment of insight in psychosis. Am. J. Psychiatry. 1993;150:873–879
  5. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th Edition. Washington, DC: American Psychiatric Association; 1994;
  6. Benazzi F. The mood disorder questionnaire for assessing bipolar spectrum disorder frequency. Can. J. Psychiatry. 2002;47:386–387
  7. Dawson B, Trapp RG. Basic and Clinical Biostatistics. 3rd Edition. New York: Lane Medical Books/McGraw Hill; 2001;
  8. Dunner DL, Tay LK. Diagnostic reliability of the history of hypomania in bipolar II and patients with major depression. Comp. Psychiatry. 1993;34:303–307
  9. Ghaemi SN, Ko JY, Goodwin FK. ‘Cade’s disease’ and beyond: misdiagnosis, antidepressant use and a proposed definition for bipolar spectrum disorder. Can. J. Psychiatry. 2002;47:125–134
  10. Ghaemi SN, Lenox ML, Baldessarini RJ. Effectiveness and safety of antidepressants in long term treatment of bipolar disorder. J. Clin. Psychiatry. 2001;62:565–569
  11. Ghaemi SN, Sachs GS, Chiou AM, Pandurangi AK, Goodwin FK. Is bipolar disorder still underdiagnosed? Are antidepressants overutilized?. J. Affect. Disord. 1999;52:135–144
  12. Ghaemi SN, Stoll AL, Pope HG. Lack of insight in bipolar disorder: the acute manic episode. J. Nerv. Ment. Dis. 1995;183:464–467
  13. Ghaemi SN, Pope HG. Lack of insight in psychotic and affective disorders: a review of empirical studies. Harv. Rev. Psychiatry. 1994;2:22–33
  14. Hirschfeld RMA, Holzer C, Calabrese JR, Weissman M, Reed M, Fyre MA, et al. Validity of the mood disorder questionnaire: a general population study. Am. J. Psychiatry. 2003;160:178–180
  15. Hirschfeld RMA, Williams JBW, Spitzer RL, Calabrese JR, Flynn L, Keck PE, et al. Development and validation of a screening instrument for bipolar: The Mood Disorder Questionnaire. Am. J. Psychiatry. 2000;157:1873–1875
  16. Keitner GI, Miller IW, Fruzzetti AE, Epstein NB, Bishop DS, Norman WH. Family functioning and suicidal behavior in psychiatric inpatients with major depression. Psychiatry. 1987;50:242–255
  17. Laje G, Peselow ED, Luff JA, Ying P, Paizis M, Fieve RR, et al. The rating for depression as assessed by clinicians, patients, and informants (abstract). In: Annual Meeting of the American Psychiatric Association, Philadelphia, PA. 2002;
  18. Miller CJ, Ghaemi SN, Klugman J, Berv DA, Pies RW. Utility of mood disorder questionnaire and bipolar spectrum diagnostic scale (abstract). In: Annual Meeting of the American Psychiatric Association, Philadelphia, PA. 2002;
  19. Passik SD, Kirsh KL, Donaghy KB, Theobald DE, Lundberg JC, Holtsclaw E, et al. An attempt to employ Zung self-rating depression scale as a ‘lab test‘ to trigger follow-up in ambulatory oncology clinics: criterion validity and detection. J. Pain Sympt. Manag. 2001;21:273–281
  20. Simpson SG, McMahon FJ, McInnis MG, MacKinnon DF, Edwin D, Folstein SE, et al. Diagnostic reliability of bipolar II disorder. Arch. Gen. Psychiatry. 2002;59:736–740
  21. Truman CJ, McNally EE, Goldberg JF. A comparison of self-ratings and observer ratings in bipolar patients (abstract). In: Annual Meeting of the American Psychiatric Association, Philadelphia, PA. 2002;

PII: S0165-0327(03)00156-3

doi: 10.1016/S0165-0327(03)00156-3

Journal of Affective Disorders
Volume 81, Issue 2 , Pages 167-171 , August 2004

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