Journal of Affective Disorders
Volume 78, Issue 3 , Pages 273-277 , March 2004

Interleukin-1β and tumor necrosis factor-α in children with major depressive disorder or dysthymia

  • F. Brambilla

      Affiliations

    • Corresponding Author InformationCorresponding author. Centro di Psiconeuroendocrinologia, Piazza Grandi 3, Milan 20129, Italy. Tel.: +39-368-301-7420; fax: +39-2-7012-2889.
  • ,
  • P. Monteleone
  • ,
  • M. Maj

Received 25 March 2002 ,Revised 5 August 2002 ,Accepted 16 August 2002.

References 

  1. APA. Diagnostic and Statistical Manual of Mental Disorders. 4th Edition. Washington, DC: American Psychiatric Association; 1994;
  2. Chambers WJ, Puig-Antich J, Hirsch M, Paez P, Ambrosini PJ, Tabrizi MA, et al. The assessment of affective disorders in children and adolescents by semistructured interview. Arch. Gen. Psychiat. 1985;42:696–702
  3. Frommberger UH, Bauer J, Haselbauer P, Fraulin A, Riemann D. Interleukin-6 (Il-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission. Eur. Arch. Psychiat. Clin. Neurosci. 1997;247:228–233
  4. Frye MA, Mathè AA, George MS, Pazzaglia PJ, Jerrels S, Post RM. CSF neuropeptide Y in mood disorders and treatment with carbamezapine. Biol. Psychiat. 1995;37:609–610
  5. Geary N. Sex differences in disease anorexia. Nutrition. 2001;17:499–507
  6. Katila H, Appelberg B, Hurme M, Rimon R. Plasma levels of interleukin-1β and interleukin-6 in schizophrenia, other psychoses and affective disorders. Schizophrenia Res. 1994;12:29–34
  7. Kronfol Z, Singh VJ, Zhang Q, Starkman M, Schteingart DE. Plasma cytokines, acute phase proteins and cortisol in major depression. Biol. Psychiat. 1995;37:609; Abstract
  8. Kudoh A, Katagai H, Takazawa T. Plasma inflammatory cytokine response to surgical trauma in chronic depressed patients. Cytokine. 2001;13:104–108
  9. Levine J, Barak Y, Chengappa KNR, Rapoport A, Rebey M, Barak V. Cerebrospinal cytokine levels in patients with acute depression. Neuropsychobiology. 1999;40:171–176
  10. Maes M, Bosmans E, Suy E, Minner B, Raus J. A further exploration of the relationship between immune parameters and the HPA axis activity in depressed inpatients. Psychol. Med. 1991;21:313–320
  11. Maes M, Bosmans E, Suy E, Vandervorst C, Dejonckheere C, Raus J. Depression-related disturbances in mitogen-induced lymphocyte responses and interleukin-1β and soluble interleukin-2 receptor production. Acta Psychiat. Scand. 1991;84:379–386
  12. Maes M, Bosmans E, Suy E, Vandervorst C, Dejonckheere C, Raus J. Antiphospholipid, antinuclear, Epstein–Barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients. J. Affect. Dis. 1991;21:133–140
  13. Maes M, Vandervorst C, Suy E, Minner B, Raus J. A multivariate study of the simultaneous urinary free cortisol, plasma cortisol, adrenocorticotropic hormone and β-endorphin escape from suppression by dexamethasone in melancholic patients. Acta Psychiat. Scand. 1991;3:480–491
  14. Maes M, Bosmans E, Meltzer HY, Scharpé S, Suy E. Interleukin-1β: a putative mediator of HPA axis hyperactivity in major depression?. Am. J. Psychiat. 1993;150:1189–1193
  15. Maes M, Meltzer HY, Stevens W, Cosyns P. The blunted natural killer cell activity in major depression is significantly related to various indices of in vivo systemic immune activation. Progr. Neuropsychopharmacol. Biol. Psychiat. 1994;18:717–730
  16. Maes M, Bosmans E, Meltzer HY. Immunoendocrine aspects of major depression. Relationship between plasma interleukin-6 and soluble interleukin-2 receptor, prolactin and cortisol. Eur. Arch. Psychiat. Clin. Neurosci. 1995;245:172–178
  17. Maes M, Meltzer HY, Bosmans E, Bergmans R, Vandoolaeghe E, Ranjan R, et al. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J. Affect. Disord. 1995;34:301–309
  18. Maes M, Vandoolaeghe E, Ranjan R, Bosmans E, Bergmans R, Desnyder R. Increased serum interleukin-1 receptor-antagonist concentrations in major depression. J. Affect. Disord. 1995;36:29–36
  19. Maes M, Meltzer HY, Buckley P, Bosmans E. Plasma soluble interleukin-2 and transferrin receptor in schizophrenia and major depression. Eur. Arch. Psychiat. Clin. Neurosci. 1995;244:325–329
  20. Maes M, Lin A, Delmeire L, VanGastel A, Kenis G, DeJongh R, et al. Elevated serum interleukin-6 (Il-6) and Il-6 receptor concentrations in post-traumatic stress disorder following accidental manmade traumatic events. Biol. Psychiat. 1999;45:833–839
  21. Marino V, Bonaccorso S, Ippoliti F, Grimaldi F, Altavilla N, Biondi M. Interferone depressione: aspetti clinici e possibile classificazione come disturbo dell’umore indotto da sostanze. Riv. Psichiatria. 1999;34:310–313
  22. Owen BM, Eccleston D, Ferrier IN, Young AH. Raised levels of plasma interleukin-1β in major and postviral depression. Acta Psychiat. Scand. 2001;103:1–3
  23. Poznanski EO, Grossman JA, Buchsbaum Y, Banegas M, Freeman L, Gibbons R. Preliminary studies of the reliability and validity of the children’s depression rating scales. J. Am. Acad. Chil. Psychiat. 1984;23:191–197
  24. Rapaport MH. Immune parameters in euthymic bipolar patients and normal volunteers. J. Affect. Disord. 1994;32:149–156
  25. Reynold CR, Richman BO. What I think that I feel: a revised measure of children’s manifest anxiety. J. Abnorm. Child Psychol. 1978;6:271–280
  26. Rothermundt M, Arolt V, Fenker J, Gutbrodt H, Peters M, Kirkner H. Different immune patterns in melancholic and nonmelancholic major depression. Eur. Arch. Clin. Neurosci. 2001;251:90–97
  27. Schwartz E, Schafer C, Bode JC, Bode C. Influence of the menstrual cycle on the LPS-induced cytokine response of monocytes. Cytokine. 1999;12:413–416
  28. Sluzewska A, Rybakowski JK, Bosmans E, Maes M, Sobieska M. Some interleukins, their receptors and α-1-acid glycoprotein as the indicators of immune activation in major depression. Behav. Pharmacol. 1995;6(Suppl. 1):66–68
  29. Sluzewska A, Rybakowski J, Bosmans E, Sobieska M, Berghmans R, Maes M, et al. Indicators of immune activation in major depression. Psychiat. Res. 1996;64:161–167
  30. Szekeres Bartho J, Barakonyi A, Par G, Polgar B, Palkovics T, Szereday L. Progesterone as an immunomodulatory molecule. Int. Immunopharmacol. 2001;1:1037–1048
  31. Tronkowski P, Mysliwska J, Lukaszuk K, Szmit E, Bryl E, Mysliwski A. Luteal phase of the menstrual cycle in young healthy women is associated with decline in interleukin 2 levels. Horm. Metab. Res. 2000;33:348–353
  32. Verhely D. Sex hormones as immunomodulators in health and disease. Int. Immunopharmacol. 2001;1:983–993
  33. Weizman R, Laor N, Podliszewski E, Notti I, Djaldette M, Bessler H. Cytokine production in major depressed patients before and after chlomipramine treatment. Biol. Psychiat. 1994;35:42–47

PII: S0165-0327(02)00315-4

doi: 10.1016/S0165-0327(02)00315-4

Journal of Affective Disorders
Volume 78, Issue 3 , Pages 273-277 , March 2004